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蒽林/地蒽酚,1143-38-0,COA

Certificate of Analysis

Product Name

Dithranol (Cas No:1143-38-0)

Batch No.

20231015

Quantity

1.0kgs

M. Date

Oct, 2023

Exp. Date

Sep, 2026

Test

Specification

Results

Description

Yellow to brownish-yellow crystalline powder

Complies

Solubility

Practically insoluble in water, soluble in

methylene chloride, sparingly soluble in

acetone, slightly soluble in ethanol(96%).

It dissolves in dilute solutions of alkali-

-hydroxides

Complies

Identification

  • Melting Point 178℃-182℃
  • (IR) Comparison: Dithranol CRS
  • The principal spot in the chromatogram

obtained in the test solution is similar in position, colour and size to the principal spot in the chromatogram obtained with reference solution on(a)

  • Examining in ultraviolet light at 365nm,the

solution shows a blue fluorescence

Complies

Loss on drying

NMT 0.5%

0.379%

Sulfated ash

NMT 0.1%

0.09%

Chlorides

NMT 100ppm

Complies

Related substances

Test-A: Impurity A(Anthrone)

Impurity B(Dantron)

Impurity C(Dithranol Dimer)

Test-B: Impurity D

(1-Hydroxy-9-anthron)

Total (Test A+Test B)

NMT 1.0%

 

NMT 1.0%

NMT 1.0%

 

NMT 2.5%

 

 

NMT 3.0%

0.001%

 

0.472%

Not detected

 

Not detected

 

 

0.473%

Assay (On dried basis)

98.5-101.0%%

99.77%

Conclusion:

 Complies with the In-house standard

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