Product Name

Dithranol (Cas No:1143-38-0)

Batch No.

20221015

Quantity

1.0kgs

M. Date

Oct, 2022

Exp. Date

Sep, 2025

Test

Specification

Results

Description

Yellow to brownish-yellow crystalline powder

Complies

Solubility

     Practically insoluble in water, soluble in

     methylene chloride, sparingly soluble in

     acetone, slightly soluble in ethanol(96%).

      It dissolves in dilute solutions of alkali-

-hydroxides

Complies

     Identification

• Melting Point 178℃-182℃
• (IR) Comparison: Dithranol CRS
• The principal spot in the chromatogram

obtained in the test solution is similar in position, colour and size to the principal spot in the chromatogram obtained with reference solution on(a)

• Examining in ultraviolet light at 365nm,the

solution shows a blue fluorescence

Complies

     Loss on drying

NMT 0.5%

0.379%

     Sulfated ash

NMT 0.1%

0.09%

     Chlorides

NMT 100ppm

Complies

      Related substances

     Test-A: Impurity A(Anthrone)

     Impurity B(Dantron)

     Impurity C(Dithranol Dimer)

     Test-B: Impurity D

     (1-Hydroxy-9-anthron)

     Total (Test A+Test B)

NMT 1.0%

NMT 1.0%

NMT 1.0%

NMT 2.5%

NMT 3.0%

0.001%

0.472%

Not detected

Not detected

0.473%

     Assay (On dried basis)

98.5-101.0%%

99.77%

     Conclusion:

 Complies with the In-house standard