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CERTIFICATE OF ANALYSIS

Product Name

Trimethoprim

Batch No.

20200525

Batch Quantity

25kgs

Net weight

25kg/drum

Manufacture date

May 25,2020

Expiry date

May 24,2022

Analysis date

May 25,2020

Release date

May 25,2020

Pharmacopoeial Standard

BP2010

ITEMS

SPECIFICATIONS

RESULTS

Characters

A white or yellowish-white powder

Yellowish-white powder

Solubility

Very slightly soluble in water, slightly soluble in alcohol, practically insoluble in ether

Very slightly soluble in water, slightly soluble in alcohol, practically insoluble in ether

Melting point

199-203℃

200.0-200.5℃

The infrared absorption spectrum

Is concordant with the spectrum of trimethoprim EPCRS

Is concordant with the spectrum of trimethoprim EPCRS

Appearance of solution

Not more intensely colored than reference solution BY7

Less intensely colored than reference solution BY7

Heavy metals

≤20ppm

<20ppm

Related substances

≤0.2%

<0.2%

Loss on drying

≤1.0%

0.2%

Sulphated ash

≤0.1%

0.02%

Assay

98.5-101.0%

99.8%

Results

The commodity meets the standard of BP2010

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